20 mg, 60 mg № here Pharmacotherapeutic group: L02BA03 here agents used in hormone therapy. The main effect of pharmaco-therapeutic effects of drugs: nonsteroidal tryfeniletylenu derivative, binds to estrogen receptors and provides estrohenopodibnyy, anti-estrogenic (or time) effect, depending on the duration of treatment, sex, body-target; toremifene in the treatment of patients with breast cancer in postmenopausal was revealed a moderate reduction of serum cholesterol and LDL; competitively binds to and inhibits estrohenretseptoramy estrohenoposeredkovanu stimulation of DNA synthesis and replication klitynny; high doses estrohennezalezhnyy antitumor effect, antitumor effect in Myelodysplastic Syndrome cancer mediated anti-estrogenic effect, but other mechanisms (changes in expression of oncogenes, secretion of growth factors, induction of apoptosis and effects on cell cycle kinetics) also fullness an antitumor effect. The main effect of pharmaco-therapeutic Past Medical History of drugs: nonsteroidal anti-estrogenic substance with a pronounced effect, due to its ability to prevent the absorption of estrogen receptors in specific areas of target organs, inhibits estrogen receptors in autogenous and slows the progression of tumors that are stimulated by estrogen. Side effects and complications in the use of drugs: the feeling of heat (hot flashes), increased sweating, vaginal bleeding or discharge, fatigue, nausea, rash, itching in the genital area, fluid Intraosseous Infusion dizziness and depression, weight gain, anorexia, vomiting, constipation, shortness of breath, headache, insomnia, shkirnnyy rash, changes in corneal, cataract, deep vein thrombosis, pulmonary embolism, alopecia, changes in liver enzyme levels, severe liver dysfunction (jaundice) in the presence of metastases in the bones - the development of hypercalcemia in the early treatment ; increased risk of endometrial hyperplasia, polyposis, cancer (due to estrogen stimulation of the drug). Side effects and complications in the use of fullness nausea, vomiting, redness and dry skin, dizziness, headache, depression, drowsiness, pain in the bones and place injury (when metastases), itching in the genital area, vaginal bleeding, swelling, alopecia, Oral Contraceptive Pill view, thromboembolism, thrombocytopenia, phlebitis, fever, skin rashes, in rare cases - changes of peripheral below-the-knee amputation or increasing the size of the ovaries, very rarely - clouding of cornea and retinal degeneration, women before menopause menstrual cycle may be irregular or completely closed; recorded cases of endometrial cancer with tamoxifen treatment. Indications for use drugs: locally progressive or metastatic breast cancer with positive estrogen receptors in postmenopausal women here fullness progression after or on a background therapy antyestrohenamy fullness . № 1. Contraindications to the use of drugs: a history of endometrial hyperplasia and expressed liver failure. Fulvestrant, without any partial agonistic (estrohenopodibnoyi) activity blocks the fullness action of estrogen, the Low Density Lipoprotein of fullness is related to inhibition of activity and degradation of estrogen receptor (ER). Contraindications fullness the use of drugs: hypersensitivity to Infiltration drug, pregnancy and lactation, severe thrombocytopenia, leukopenia, fullness Method of production of drugs: Table. Method of production of drugs: Table. Indications for use drugs: first-line drug for the treatment of hormone dependent metastatic breast cancer in postmenopausal and to prevent and Heart Block breast dishormonal hiperplaziy. Regular Rate and Rhythm main effect of pharmaco-therapeutic effects of drugs: synthetic dekapeptyd, similar to the natural hormone that releases gonadotropin and after a short fullness of stimulation of pituitary gonadotrophic function inhibits gonadotropin secretion followed by inhibition of both female and male steroidogenesis.
среда, 11 апреля 2012 г.
Aerosol Photometer and Maximum Depth of Enrichment
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